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Table 1 Prevalence and odds ratios of five genetic variants for colorectal cancer susceptibility.

From: Sample size requirements to detect the effect of a group of genetic variants in case-control studies

Genetic variants Risk group Genotype prevalence% Odds ratio
HRAS1 (1) Rare allele vs. others 4.0 2.67
GSTT1 (2) Null vs. others 37.6 1.37
TNF-α (3) α2 allele vs. others 39.2 2.02
NAT2 [imputed from phenotype] (4) Fast acetylation vs. others [60.3] 1.68
MTHFR (5) Wild-type vs. variant (C677T) 42.3 1.35
  1. (HRAS1 = c-Ha-ras1 proto-oncogene; GSTT1 = glutathione S-transferase theta 1; TNF-α = tumor necrosis factor alpha-chain; NAT2 = N-acetyl transferase-2 gene; MTHFR = 5,10-methylenetetrahydrofolate reductase gene.)