From: Sample size requirements to detect the effect of a group of genetic variants in case-control studies
| Genetic variants | Risk group | Genotype prevalence% | Odds ratio |
|---|---|---|---|
| HRAS1 (1) | Rare allele vs. others | 4.0 | 2.67 |
| GSTT1 (2) | Null vs. others | 37.6 | 1.37 |
| TNF-α (3) | α2 allele vs. others | 39.2 | 2.02 |
| NAT2 [imputed from phenotype] (4) | Fast acetylation vs. others | [60.3] | 1.68 |
| MTHFR (5) | Wild-type vs. variant (C677T) | 42.3 | 1.35 |