From: On hazard ratio estimators by proportional hazards models in matched-pair cohort studies

Model | Analysis set | Target HR | HR estimate | 95% CI | |
---|---|---|---|---|---|

Stratified Cox model^{a}
| Matched cohort |
Conditional^{e}
| 1.47 | 1.18 | 1.83 |

Unstratified Cox model^{b}
| Matched cohort |
Marginal^{e}
| 1.33 | 1.13 | 1.57 |

IPW Cox model^{c}
| Original cohort |
Marginal^{f}
| 1.32 | 1.07 | 1.62 |

Multivariable Cox model^{d}
| Original cohort |
Conditional^{f}
| 1.48 | 1.27 | 1.71 |

IPW multivariable Cox model^{c,d}
| Original cohort |
Conditional^{f}
| 1.58 | 1.28 | 1.96 |

Unadjusted Cox model | Original cohort | Biased | 0.84 | 0.75 | 0.95 |