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Table 2 Expected number of disease cases in each study arm as a function of disease probability and individual study sample size

From: Cannons and sparrows: an exact maximum likelihood non-parametric test for meta-analysis of k 2 × 2 tables

Disease/condition Approximate disease probability Individual study sample size (each arm)
100 500 1000
Myocardial infarction .0025 .25 1.25 2.5
Parkinson’s disease (60–65 age group) .00039 .039 .195 .39
Alzheimer’s disease (60–65 age group) .0008 .08 0.4 0.8
Overall cancer for men .0055 .55 2.75 5.5